Validation and application of a canine-specific automated high-sensitivity C-reactive protein assay
نویسندگان
چکیده
منابع مشابه
Validation of a commercially available automated canine-specific immunoturbidimetric method for measuring canine C-reactive protein
BACKGROUND Measurement of C-reactive protein (CRP) is used for diagnosing and monitoring systemic inflammatory disease in canine patients. An automated human immunoturbidimetric assay has been validated for measuring canine CRP, but cross-reactivity with canine CRP is unpredictable. OBJECTIVE The purpose of the study was to validate a new automated canine-specific immunoturbidimetric CRP meth...
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C-reactive protein (CRP) is a sensitive and specific marker of systemic inflammation in dogs, valuable for diagnosing and monitoring inflammatory diseases. The use of CRP in canine medicine has however been hampered by the lack of automated assays optimized for measuring CRP in this species. The need for improved CRP assays was the reason for initiating the current project, with the goal to gen...
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BACKGROUND Prospective studies have shown that C-reactive protein (CRP) can be used to predict risk of future cardiovascular events. High-sensitivity methods for CRP (hs-CRP) measurement are needed for this purpose. METHODS We compared the clinical efficacy of an automated and commercially available latex-enhanced assay (Latex) for hs-CRP (Dade Behring) to a validated in-house ELISA, previous...
متن کاملEvaluation of a novel quantitative canine species-specific point-of-care assay for C-reactive protein
BACKGROUND Species-specific point-of-care tests (POCT) permit a rapid analysis of canine C-reactive protein (CRP), enabling veterinarians to include CRP in clinical decisions. Aim of the study was to evaluate a novel POCT for canine CRP (Point Strip™ Canine CRP Assay) run on a small in-house-analyzer (Point Reader™ V) using lithium heparin plasma and to compare assay performance to an already e...
متن کاملHigh-Sensitivity C-Reactive Protein and Cancer
BACKGROUND High-sensitivity C-reactive protein (hs-CRP) is a commonly used inflammatory marker. The association between hs-CRP and cancer is less consistent than that between hs-CRP and cardiovascular diseases. This study explored the association between hs-CRP and cancer, using a large database of Korean health examination records. METHODS A total of 80,781 Koreans who visited the health pro...
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ژورنال
عنوان ژورنال: Journal of Veterinary Diagnostic Investigation
سال: 2015
ISSN: 1040-6387,1943-4936
DOI: 10.1177/1040638715575751